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Diabete / Diamicron MR / 400 pilules de Brand Diamicron MR (Gliclazide) * 60 mg.
Laboratoire: Serdia
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DIAMICRON MR: a new approach to the treatment of type 2 diabetes
Diabetes represents a key therapeutic area for SERVIER, through a long-term cooperation with the major international diabetes associations, helping to improve diabetes care for millions of patients worldwide.
Discovered by Servier research, DIAMICRON MR is an innovative, once-daily oral antidiabetic which belongs to the class of sulfonylureas. Sulfonylureas are the most widely used antidiabetic agents worldwide and were recently recognized by the IDF Global Guidline 2005 as a cornerstone of type 2 diabetes treatment, from the early stages in monotherapy to the late stages, in combination with other agents or with insulin.
As a global metabolic and vascular approach to type 2 diabetes treatment, DIAMICRON MR provides effective glycemic control over 24 hours and in the long term, strengthened by its protective effects on pancreatic ß-cells and its direct cardiovascular benefits.
DIAMICRON MR allows a once-daily dosage, regardless of the daily dose, due to its innovative hydrophilic matrix which is used for the first time in diabetology. This modified-release formulation is designed to match the release of active ingredient with circadian hyperglycemic profile and thus offers an effective blood glucose control round-the-clock. The choice of once-daily therapy is a key factor to improving patient compliance.
Moreover, DIAMICRON MR shows the highly selective, freely reversible, and high-affinity interaction with ß-cell sulfonylurea receptors, which explains both its optimized cardiovascular acceptability, reduced risk of hypoglycemia, efficient secretagogue effect, and unsurpassed long-term glycemic control of this agent.
Beyond effective glycemic control, DIAMICRON MR provides unique antioxidant properties11,12 which explain the preservation of ß-cells fuction12,13, the beneficial effect on endothelial function. and a potent antiatherogenic effect.
Altogether, these unique features of DIAMICRON MR account for its capacity to reduce the risk of myocardial infarction and to increase the chances of survival following an acute event.
The excellent efficacy and acceptability of DIAMICRON MR, 2 to 4 tablets once daily, teamed with its additional benefits, promise to improve vascular outcomes for type 2 diabetic patients, and have led to choose it for ADVANCE study, the biggest ever prospective morbidity/mortality study in type 2 diabetes.
Attached References
DIAMICRON MR is also distributed as:
Diabeton MR, Diamicron 30mg, Diamicron LM 30mg, Diamicron MR 30 mg, Diamicron Uno 30mg, Dianormax MR, Diaprel MR and Uni Diamicron. | |
