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Generic Name: Mebeverine
Brand Name: Colofac
How does it work?
Colofac tablets contain the active ingredient mebeverine hydrochloride, which is a type of medicine called an antispasmodic. (NB. Mebeverine tablets are also available without a brand name, ie as the generic medicine.)
Mebeverine works by acting directly on the smooth muscle in the gut, causing it to relax. This relieves painful muscle spasms of the gut, without affecting it's normal motility.
Mebeverine is used to relieve symptoms of irritable bowel syndrome and related intestinal disorders that are the result of spasms in the intestinal muscles. These include colicky abdominal pain and cramps, diarrhoea alternating with constipation and flatulence (wind).
The medicine is taken three times a day, preferably 20 minutes before meals, as this will help relieve symptoms that are worse after eating. When the symptoms have improved, usually after several weeks, the dose can be gradually reduced.
What is it used for?
· Irritable bowel syndrome
Use with caution in
· Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias)
Not to be used in
· This medicine is not recommended for children under 10 years of age.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
· This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than any possible risk to the foetus. Seek medical advice from your doctor.
· This medicine passes into breast milk, but the amount is considered too small to be harmful to a nursing infant. Seek further medical advice from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
· Rarely, allergic reactions such as rashes or severe swelling of lips, face or tongue (angioedema)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
This medicine is not known to interact with other medication. | 
